clinical use of hyaluronic acid plus silver sulfadiazine for wound healing in diabetes

Impaired wound healing in diabetes: the rationale for clinical use of hyaluronic acid plus silver sulfadiazine

Article specifications

This Review Study was published in 2012 in Minerva Medica Journal (IF 2013:1.202) by Italian specialists. The pri­mary objective of this review is to analyze the most recent evidence supporting the clinical use of a formulation containing hyaluronic acid (HA) and silver sulfadiazine (SSD) in the diabetic patient. This formulation has been widely used in cutaneous lesions of various etiology, both acute and chronic.



HA use in the clinical setting is well es­tablished, indeed an overall positive effect of HA can be expected in the healing of chronic wound ulcers of various etiolo­gies, burns, and epithelial surgical wounds, no matter the form in which HA is deliv­ered topically. Coupling the considerations regarding HA activity on tissue repair in diabetes with those supporting SSD application in various types of wounds to control microbial pro­liferation, it appears that simultaneous ap­plication of SSD and HA may be a rational choice for the treatment of chronic lesions affecting diabetic patients.

Tags: Italy Minerva Medica Review article 2012

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