Evaluate the decrease in metatarsalgia using a hyaluronic acid dermal filler

Hyaluronic Acid Filler Injections Under the Metatarsal Heads Provide a Significant and Long-Lasting Improvement in Metatarsalgia from Wearing High-Heeled Shoes

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This clinical trial was published in 2018 in Journal of Dermatol Surg. (IF2014: 2.109) by French specialists. The aim of the present study was to evaluate the decrease in metatarsalgia using a hyaluronic acid dermal filler. This study involved unlabeled/investigational use of RES Kysse. The injectable gel formulation consisted of 20mg/mL of HA with 3 mg/mL of lidocaine. Each injection of filler treatment was preceded by an injection of local anesthetic (0.2 mL lidocaine 10 mg/mL with adrenaline). A retrograde or anterograde linear threading technique (bolus injections) was performed at the discretion of the investigator, with subdermal injection into the hypodermis.



Injection of hyaluronic acid filler to the forefeet provided a significant effective, long-lasting, and well-tolerated improvement in metatarsalgia because of wearing high-heeled shoes.

Tags: France Clinical trial 2018 .Dermatol Surg

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