Effect of hyaluronic acid on postoperative radiofrequency surgery for chronic inferior turbinate hypertrophy

Effect of hyaluronic acid on postoperative radiofrequency surgery for chronic inferior turbinate hypertrophy.jpg

The potential role of hyaluronic acid in postoperative radiofrequency surgery for chronic inferior turbinate hypertrophy

Article specifications

This prospective, randomized study was published in 2013 in American Journal of Rhinology & Allergy (IF 2016:1.955) by Italian and Spanish and Croatian specialists. This study evaluated the efficacy of hyaluronic acid (HA) as an adjuvant treatment to hasten the improvement of nasal respiration and to minimize patients’ discomfort in the postoperative radiofrequency volumetric tissue reduction (RFVTR) of inferior turbinates.  This study enrolled 57 patients assigned into two groups:

  1. The HA group (22 patients; 8 women and 14 men; mean age, 45 years; range, 18–72 years), which included patients who received HA 3 mL of HA is dissolved in 2 mL of isotonic solution twice a day through Rinowash (a nebulizer designed to treat upper airway structures, creating micronized particles),
  2. The saline group (35 patients; 14 women and 21 men; mean age, 42 years; range, 18–75 years) received normal saline nasal irrigation twice a day.

We used the monopolar device somnoplasty for all patients. Visual analogic scale (VAS) and nasal endoscopy were used to assess the outcomes of the treatments during the 1st month of follow-up.

 

Results

The mean VAS score of the HA group at the 1st week was significantly lower than the control group. The VAS score remained significantly lower in the HA group also at the 2nd week, becoming similar to the control group at the 4th week. Since the first visit the HA group also showed significantly lower crust score than the saline group, and there was no crust found in either group at the last visit. The compliance to treatment was similar in both groups. The results of this study suggest a role of HA as a supportive treatment for faster improvement of nasal respiration, also minimizing patients’ discomfort in postoperative nasal surgery, promoting nasal mucosa healing in postoperative RFVTR for inferior turbinate hypertrophy.

Tags: Italy Spain Am J Rhinol. Allergy Clinical trial 2013

Hayland Center

© 2018 HYLAND.CENTER ALL RIGHTS RESERVED