A low-fat yoghurt supplemented with a rooster comb extract on muscle joint function in adults with mild knee pain: a randomized, double blind, parallel, placebo-controlled, clinical trial of efficacy.
A low-fat yoghurt supplemented with a rooster comb extract on muscle joint function in adults with mild knee pain: a randomized, double blind, parallel, placebo-controlled, clinical trial of efficacy.
Article specifications
This randomized, double blind, parallel, placebo-controlled, clinical trial was published in 2015 Food and Function journal (IF 2015:2.89) by Spanish specialists. The objective of this study was to evaluate the effect of low-fat yoghurt supplemented with rooster comb extract (RCE) rich in HA on muscle function in adults with mild knee pain; a symptom of early osteoarthritis. Participants (n = 40) received low-fat yoghurt (125 mL d−1) supplemented with 80 mg of RCE and the placebo group (n = 40) consumed the same yoghurt without the RCE, over 12 weeks. The RCE was extracted from food grade rooster combs using an extraction process. To guarantee the appropriate dosage, the RCE was added before yogurt fermentation in the manufacture process. The participants’ diets were monitored using two 3-day dietary records, one prior to commencing the study, and the other at 12 weeks of the trial. Additionally, a list of foods and products rich in mucopolysaccharides and/or HA was provided to the participants with instructions to avoid these dietary items so as to preempt their influence on the test substance measurements.
Results
Using an isokinetic dynamometer (Biodex System 4), RCE consumption, compared to control, increased the affected knee peak torque, total work and mean power at 180° s−1, at least 11% in men with no differences in women. No dietary differences were noted. These results suggest that long-term consumption of low-fat yoghurt supplemented with RCE could be a dietary tool to improve muscle strength in men, including better performance of the quadriceps and hamstring muscles of the knee. However, further studies are needed to elucidate reasons for these sex difference responses observed, and may provide further insight into muscle function.
