Efficacy and safety of the topical application of 0.2% HA gel on recurrent oral ulcers and to compare its effects in patients with recurrent aphthous ulcers (RAU) and the oral ulcers of Behçet's disease

The efficacy of topical 0.2% hyaluronic acid gel on recurrent oral ulcers comparison between recurrent aphthous ulcers and the oral ulcers of Behçet's disease.

Article specifications

This clinical study was published in 2008 in Journal of J Eur Acad Dermatol Venereol. (IF 2008: 0.33) by Korean specialists. The purpose of this study was to observe the efficacy and safety of the topical application of 0.2% HA gel on recurrent oral ulcers and to compare its effects in patients with recurrent aphthous ulcers (RAU) and the oral ulcers of Behçet's disease (BD). Thirty-three outpatients with recurrent oral ulcers were included in the study (17 patients: BD, 16 patients: RAU). The patients used topical 0.2% HA gel twice daily for 2 weeks.

 

Result

The topical application of 0.2% HA gel seems to be an effective and safe therapy in patients with recurrent oral ulcers; the study supports the use of HA in BD with oral ulcers.