The use of different HA-based products in patients with chronic skin ulcers of various etiologies (vascular, scleroderma, postoperative) to assess the indication, effectiveness, and possible adverse reactions

Hyaluronic Acid-based Products are Strictly Contraindicated in Scleroderma-related Skin Ulcers.

Article specifications

This case review study was published in 2019 in Journal of Wounds. (IF 2013:0.53) by Italian specialists. This retrospective, observational study examined the use of different HA-based products in patients with chronic skin ulcers of various etiologies (vascular, scleroderma, postoperative) to assess the indication, effectiveness, and possible adverse reactions.

 

Result

The negative effects of HA-based products on a patient with scleroderma could be explained by the fact that HA can produce a proinflammatory effect causing keratinocyte migration.

Tags: Italy Review article 2019 Wounds

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