The effect of exogenous intradermal HA during deep dermal, incisional wound healing

Hyaluronic Acid Accelerates Re-epithelialization and Alters Protein Expression in a Human Wound Model

Article specifications

This clinical trial was published in 2019 in Journal of PRS Global Open by Swedish specialists. The purpose of this study was to investigate the effect of exogenous intradermal HA during deep dermal, incisional wound healing in vivo in humans, the primary endpoint being re-epithelialization.

 

Results

We conclude that HA accelerates re-epithelialization and stimulates an altered protein expression in vivo in human deep dermal incisional skin wounds, but has no effect on the inflammation process as measured by erythema.