Perceived Efficacy of Vaginal Dryness Relief: A Comparative Clinical Study between Sodium hyaluronate vaginal gel1 vs. hormonal cream Promestriene cream.
This Open-label, prospective, randomized and controlled clinical trial was published in 2017 in journal of Advances in Sexual Medicine (IF 2015:0.26) by Brazilian gynecologists. In this study efficacy of the sodium hyaluronate gel vaginal application and hormonal cream promestriene which were tested to treat the gynecological symptoms of people who suffered from vaginal dryness were evaluated. 74 female participants were recruited for the study, with ages between 42 and 67 years. 35 patients applied sodium hyaluronate vaginal gel one time a day for a period of two times a week during three weeks and other 33 patients using promestriene cream applied it every day for a period of three weeks. The comparison between the treatments was performed using the nonparametric Mann-Whitney test. The evaluation of the efficacy was carried out through the application of Perceived Efficacy questionnaires based on the “Standard Guide for Sensory Claim substantiation” of the American Society for Testing and Materials (ASTM).
This evaluation study of the Perceived Efficacy as therapeutic innovation-Lubrinat® (sodium hyaluronate) supports its use in the initial approach of symptoms of vaginal dryness, according to the North American Menopause Society (NAMS) 2013 position statement which says the primary goal of treating symptomatic vulvovaginal Atrophy (VVA). Vaginal dryness can be helped by Lubrinat® (sodium hyaluronate). It’s the most logical treatment to use in vaginal dryness since it’s a modern, biotech, safe and well-tolerated product.