Changes in pain, disability, and medication usage over time after facet joint injection of hylan G-F 20.

Prospective pilot study of painful lumbar facet joint arthropathy after intra-articular injection of hylan G-F 20.

Article specifications

This clinical trial was published in 2009 in Journal of PM R. (IF 2015: 1.53) by American specialists. The study aim was to examine changes in pain, disability, and medication usage over time from baseline to up to 12 months after facet joint injection of hylan G-F 20. Fifteen patients (12 females), mean age of 57 years, with a median duration of low back pain of 24 months.

 

Result

Viscosupplementation for lumbar FJ arthropathy with hylan G-F 20 is associated with modest efficacy that predominately lasts up to 6 months. Limitations include a small sample size and lack of both a control and blinding. Larger, randomized, controlled studies are indicated to better clarify its clinical safety, efficacy, and utility.