Efficacy and safety of intraarticular sodium hyaluronate (SH) compared with intraarticular glucocorticoids (triamcinolone acetonide; TA) in the treatment of chronic nonradicular lumbar pain

Intraarticular hyaluronic acid versus glucocorticoid injections for nonradicular pain in the lumbar spine.

Article specifications

This clinical trial was published in 2005 in Journal of J Vasc Interv Radiol. (IF 2015: 0.13) by German specialists. The study aim was to investigate the efficacy and safety of intraarticular sodium hyaluronate (SH) compared with intraarticular glucocorticoids (triamcinolone acetonide; TA) in the treatment of chronic nonradicular lumbar pain. Sixty patients were included in this randomized, controlled, blind-observer clinical study and randomly assigned to two groups to receive 10 mg SH or 10 mg TA per facet joint. The facet joints on both sides at levels S1-L5, L5-L4, and L4-L3 were treated once per week under computed tomographic guidance.

 

Result

Patients reported lasting pain relief, better function, and improved quality of life with both treatments. Intraarticular SH is a very promising new option for the treatment of patients with chronic nonradicular lumbar symptoms.