Evaluating the use of intra-articular injections as a treatment for painful hip osteoarthritis

Evaluating the use of intra-articular injections as a treatment for painful hip osteoarthritis: a randomized, double-blind, multicenter, parallel-group study comparing a single 6-mL injection of hylan G-F 20 with saline.

Article specifications

This clinical trial was published in 2018 in Journal of Osteoarthritis Cartilage. (IF 2014:4.165) by Canadian and American specialists. The aim of this study was to compare safety/efficacy of a single, 6-mL image-guided injection of hylan G-F 20 to saline in painful hip OA. 357 patients were enrolled in a multicenter, double-blind, randomized saline placebo- controlled trial.

 

Result

A single 6-mL hylan G-F 20 injection or saline for painful hip OA resulted in similar, statistically significant/clinically relevant pain and function improvements up to 6 months following injection; no differences between hylan G-F 20 and saline placebo were observed.

Tags: USA Canada osteoarthritis and cartilage Clinical trial 2018

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