Intra-articular hyaluronic acid in the treatment of knee osteoarthritis
Intra-articular hyaluronic acid in the treatment of knee osteoarthritis: a Canadian evidence-based perspective
Article specifications
This review study was published in 2017 in Journal of Ther Adv Musculoskelet Dis. (IF 2014:4.81) by Canadian specialists. Outcomes from a total of eight MAs were reviewed, and consistent and statistically significant improvements in pain, function and stiffness up to 26 weeks were found with IAHA therapy compared with IA placebo or controls, regardless of MA size or trial quality.
Result
The results of this study showed that IAHA therapy is a well-tolerated and effective option for patients with mild-to-moderate knee OA failing first-line pharmacological therapy.