Exploring determinants predicting response to intra-articular hyaluronic acid treatment in symptomatic knee osteoarthritis

Exploring determinants predicting response to intra-articular hyaluronic acid treatment in symptomatic knee osteoarthritis: 9-year follow-up data from the Osteoarthritis Initiative.

Article specifications

This study was published in 2018 in Journal of Arthritis Res Ther. (IF 2017:4.269) by Canadian specialists. This study aimed at identifying determinants associated with a better response to IAHA treatment in knee OA. Participants (n = 310) received a total of 404 treatments (one per knee).

 

Result

This study identified reliable predictive determinants that can distinguish patients who could best benefit from IAHA treatment: high levels of knee pain, younger, and less severe structural damage. These could be implemented in clinical practice as a useful guide for physicians.