Effect of multiple intra-articular injections of polynucleotides on treatment of intractable knee osteoarthritis

Effect of multiple intra-articular injections of polynucleotides on treatment of intractable knee osteoarthritis

Article specifications

This case report study was published in 2017 in Journal of Medicine (IF 2016: 2.133) by Korean specialists. A 61-year-old female was admitted to the pain center with symptoms of pain over the knee and warmth feeling with stiffness in the left knee. The patient reported chronic severe pain in the left knee area despite 6 times IAI of HA. She had received IAI of HA 6 times in 3 months and NSAIDs for intractable pain of the medial knee. Ultrasound-guided IAI of PN was carried out 3 times in 3 weeks.

 

Result

She was followed-up for more than 5 months with good improvement in intractable knee pain without any adverse event. IAI of PN is an efficient therapeutic option for KOA treatment if HA injection is unsuccessful.