Efficacy and tolerability of intra-articular injections with the GO-ON® matrix, a new product made of non-animal sodium hyaluronate combined with the oxygen free radical scavenger sorbitol

Safety and Efficacy Findings from a Non-interventional Study of a New Hyaluronic Acid Sorbitol Formulation (GO-ON® Matrix) for Intra-articular Injection to Relieve Pain and Disability in Osteoarthritis Patients

Article specifications

This clinical study was published in 2013 in Journal of Drug Res. (IF 2014:0.701) by German specialists. This non-interventional study was intended to examine the efficacy and tolerability of intra-articular injections with the GO-ON® matrix, a new viscosupplement product made of non-animal sodium hyaluronate combined with the oxygen free radical scavenger sorbitol, when used in routine clinical practice. A total of 1 147 patients aged on average 63.3 years with osteoarthritis were enrolled in 398 centers and treated with the product. Most patients (58–66%, imputing for missing data) received 1 injection, 29–40% received 3 injections.

 

Results

The results confirm that the GO-ON matrix® treatment is effective and well tolerated in the treatment of symptoms due to osteoarthritis. No infections were reported in any treated joints.

Tags: Germany Clinical trial 2013 Drug Des Devel Ther

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