The safety of repeat courses of SUPARTZ injections for knee OA

Safety of Repeated Injections of Sodium Hyaluronate (SUPARTZ) for Knee Osteoarthritis: A Systematic Review and Meta-Analysis

Article specifications

This Systematic Review was published in 2016 in Journal of Cartilage. (IF 2016: 1.00) by American specialist. A systematic search of MEDLINE, Cochrane database, EMBASE, Web of Science, Google Scholar, and unpublished data.

 

Results

Adverse events to SUPARTZ are rare in patients who have already received one course of SUPARTZ therapy. Data suggest subsequent courses of injections are at least as safe, and probably safer, than the first course. There is no evidence of increased risk associated with a high frequency of SUPARTZ use. Thus, this study provides necessary and sufficiently valid scientific evidence to offer reasonable assurance of the safety of SUPARTZ for multiple courses of injection.