Compare the efficacy of intra-articular PRP vs hyaluronic acid injections in treating haemophilic arthropathy of knee joints

An exploratory comparison of single intra-articular injection of platelet-rich plasma vs hyaluronic acid in treatment of haemophilic arthropathy of the knee.

Article specifications

This clinical trial was published in 2019 in Journal of Haemophilia. (IF 2018: 1.42) by Taiwan specialists. This study aimed to compare the efficacy of intra-articular PRP vs hyaluronic acid (HA) injections in treating haemophilic arthropathy of knee joints. Twenty-two haemophilia patients with painful haemophilic arthropathy of the knee were enrolled for this open-label and observer-blind study.

 

Result

The result of this study shows that, in comparison with five weekly injections of HA, a single PRP injection resulted in better improvement in pain relief and knee joint function, and greater reduction in synovial hyperaemia for up to 6 months. Our results suggest that PRP may be practical and effective for haemophilic knee arthropathy, and further investigation is warranted.  

Tags: Taiwan Clinical trial 2019 Haemophilia

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