Effectiveness and safety of intra-articular sodium hyaluronate (Ostenil®mini) compared to intra-articular triamcinolone acetonide (Trigon depot®) in the treatment of painful hallux rigidus

Sodium Hyaluronate in the treatment of Hallux Rigidus. A Single-Bind, randomized study

Article specifications

This clinical trial was published in 2007 in journal of Foot & Ankle International (IF2018: 1.35) by Spanish specialists. The purpose of this study was to evaluate the effectiveness and safety of intra-articular sodium hyaluronate (Ostenil^®mini) compared to intra-articular triamcinolone acetonide (Trigon depot^®) in the treatment of painful hallux rigidus. Patients were randomly allocated into two groups and received a single intra-articular injection of either 1.0 ml SH (Ostenil^®mini) or 1.0 ml TA (Trigon depot^®) into the MTP joint.

 

Results

In conclusion, an intra-articular injection of sodium hyaluronate or triamcinolone acetonide in patients with hallux rigidus resulted in a decrease in pain and an improvement in function at 3 months after the injection. However, the difference in pain relief was significantly better in the SH group at days 28 and 56. However, it should be noted that at 1-year follow-up a high percentage of patients in both groups had required surgery because of continued pain and reduced function (SH, 46.6%, TA 52.9%).