Compare patients who received preoperative corticosteroid or hyaluronic acid injections and to determine whether a specific injection type increased the risk of periprosthetic joint infection

Efficacy and Safety of Intra-articular Injections of Hyaluronic Acid Combined With Polydeoxyribonucleotide in the Treatment of Knee Osteoarthritis.

Article specifications

This original article was published in 2019 in Journal of Ann Rehabil Med. (IF 2018: 0.55) by Korean specialists. The aim of this study was to assess the clinical efficacy and safety of intra-articular injection of hyaluronic acid (HA) combined with polydeoxyribonucleotide (PDRN) in patients with knee osteoarthritis in comparison with that of HA alone.

 

Results

Intra-articular injections of HA combined with PDRN might be useful in enhancing the efficacy of HA alone in the treatment of knee OA. However, our results cannot be generalized as we evaluated a small number of patients who were treated at a single, secondary medical institution. Apparently, we could not completely rule out the possibility of selection bias.