Effectiveness and safety of Fermathron plus in patients with mild to moderate knee osteoarthritis

No difference between intra-articular injection of hyaluronic acid and placebo for mild to moderate knee osteoarthritis a randomized, controlled, double-blind trial.

Article specifications

This study was published in 2015 in Journal of J Arthroplasty. (IF2015: 3.55) by Netherlands specialists. The main goal of our study was to examine the effectiveness and safety of Fermathron plus, a specific brand of hyaluronic acid (HA), in patients with mild to moderate knee osteoarthritis.

 

Results

Although pain and functional scores (WOMAC scale) improved significantly from baseline up to 6 months, HA was not superior to placebo at any follow-up. No subgroup analysis resulted in superior outcomes. No serious adverse events were noticed.   

Tags: Netherland 2015 J Arthroplasty

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