Compare the effect of lyophilized amniotic membrane, application of hyaluronic acid, and their combination in preventing peritendinous adhesion after tendon repair
Effect of lyophilized amniotic membrane, hyaluronic acid, and their combination in preventing adhesion after tendon repair in New Zealand white rabbits
Article specifications
This clinical trial was published in 2014 in Journal of Med J Indones (IF 2015:0.19) by Indonesian specialists. This study aimed to compare the effect of lyophilized amniotic membrane, application of hyaluronic acid, and their combination in preventing peritendinous adhesion after tendon repair in New Zealand white rabbits. 64 flexor digitorum fbularis tendon from 16 rabbits were cut and then repaired by modifed Kessler technique. Samples were allocated into four test groups; group I as control had simple tendon repair, group II had amniotic membrane wrapping at repair site, group III had hyaluronic acid application at repair site, and group IV had combination of amniotic membrane wrapping and hyaluronic acid application.
Result
The application of lyophilized amniotic membrane, hyaluronic acid, or their combination significantly reduce the formation of peritendinous adhesion in repaired flexor digitorum fibularis tendon in rabbit model.