Effect of hyaluronic acid (HA) in the tendon–bone healing process after rotator cuff repair in a rabbit model
Enhancement of rotator cuff tendon–bone healing using bone marrow–stimulating technique along with hyaluronic acid
Article specifications
This clinical trial was published in 2019 in Journal of Orthopedic Translation (IF 2017: 2.95) by Chinese specialists. The purpose of this study was to investigate the effect of hyaluronic acid (HA) in the tendon–bone healing process after rotator cuff repair in a rabbit model. In vitro, rat bone marrow stromal cells (rBMSCs) were cultured in media for cartilage-related and inflammation-related gene expression levels examination at 1.0 mg/mL of HA.
Results
HA may play a crucial role in the acceleration of tendon-to-bone healing which might be through inhibiting inflammation. Rotator cuff repair using MF along with HA led to better tendon–bone healing and a subsequent increase of biomechanical strength at the repair site.