Comparison of hyaluronan and fibronectin in the healing of tympanic membrane perforations

A comparison of hyaluronan and fibronectin in the healing of tympanic membrane perforations.

Article specifications

This clinical trial was published in 1991 in journal of Eur Arch Otorhinolaryngol. (IF2011: 1.80) by Swedish specialists. The perforations occupied the upper, posterior quadrant of the TM. Saline-treated and untreated perforations of equal size served as controls. Fifty percent of the perforations treated daily with hyaluronan healed prior to the first closures of the other groups.

 

Results

These findings indicate that exogenously applied hyaluronan could be valuable in the clinical situation and should be tried to improve the healing of TM perforations.