Compare the outcomes of spontaneous closure and hyaluronic acid (HA) ester patching (Epifilm®) in subjects with traumatic tympanic membrane (TM) perforation

A prospective controlled trial comparing spontaneous closure and Epifilm^® patching in traumatic tympanic membrane perforations.

Article specifications

This clinical trial was published in 2013 in Eur Arch Otorhinolaryngol. (IF2013: 1.63) by Turkish specialists. The objective was to compare the outcomes of spontaneous closure and hyaluronic acid (HA) ester patching (Epifilm^®) in subjects with traumatic tympanic membrane (TM) perforation. During 6-month period, subjects were divided into spontaneous closure (group A) and HA ester patch-Epifilm® (group B) group.

 

Results

HA ester patch (Epifilm^®) is a non-toxic material that can be used in traumatic tympanic membrane perforations. Use of HA ester patching was resulted with earlier closure time but not resulted with higher closure rates.