Antiadhesive and antibiofilm activity of hyaluronic acid toward bacterial species commonly isolated from respiratory infections

Antiadhesive and antibiofilm activity of hyaluronic acid against bacteria responsible for respiratory tract infections.

Article specifications

This clinical trial was published in 2014 in Journal of APMIS (IF 2014:2.18) by Italian specialists. This study aimed to evaluate the in vitro antiadhesive and antibiofilm activity of hyaluronic acid toward bacterial species commonly isolated from respiratory infections.

 

Results

In conclusion, hyaluronic acid is characterized by notable antiadhesive properties, while it shows a moderate activity against bacterial biofilm. As bacterial adhesion to oral cells is the first step for colonization, these results further sustain the role of hyaluronic acid in prevention of respiratory infections.