Treatment of nasal inflammatory diseases with LYO HA-CL - SAP

In vitro characterization of physico-chemical properties, cytotoxicity, bioactivity of urea-crosslinked hyaluronic acid and sodium ascorbyl phosphate nasal powder formulation.

Article specifications

This original article was published in 2019 in Journal of Int J Pharm. (IF 2017: 3.862) by Italian specialists. The aim was to understand if lyophilized dry powder formulation consisting of urea-crosslinked hyaluronic acid (HA-CL) and sodium ascorbyl phosphate (LYO HA-CL – SAP) could be used as adjuvant treatment for nasal inflammatory diseases.

 

Results

The results suggest that HA-CL and SAP had anti-inflammatory activity and acted in combination to accelerate wound healing. Therefore, LYO HA-CL - SAP could be a potential adjuvant in nasal anti-inflammatory formulations.

Tags: Italy Int J Pharm Original research 2019

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