Assess the risk of bias (RoB) of systematic reviews (SRs) and to summarize available evidence of HA in treating knee OA Intra-articular hyaluronic acid injection in treating knee osteoarthritis: assessing risk of bias in systematic reviews with ROBIS tool.
Evaluate the therapeutic trajectory of intra-articular injections of hyaluronic acid at high concentration (2%) performed at 4-month intervals Hyaluronic acid in knee osteoarthritis: preliminary results using a four months administration schedule.