Systematic Review articles of Hyaluronic acid effects on wound healing

The Role of Hyaluronic Acid in Wound Healing

Article specifications

This review article was published in 2005 American Journal of Clinical Dermatology (IF 2015: 2.755) by British specialists. This study presents an overview, including the scientific evidence for its use in wound healing. It used the experience of this technology with searches in the English language literature for the purpose of a systematic review. It summarizes the evidence for and against hyaluronic acid and provide a resume´ of the current technologies available in fields such as skin regeneration and wound healing, in addition to cosmetic surgery.

 

Results

Hyaluronic acid is a naturally occurring polymer with a highly conserved molecular structure. It has been used extensively in a number of fields, including ophthalmic and joint surgery and particularly wound healing. Hyaluronic acid has important rheostatic and viscosity-controlling properties as a macromolecule, and its degradation products have important modulating effects on the healing wound. It enhances keratinocyte proliferation and migration, as well as the angiogenic response from the wound bed. Although the material is not the panacea against all evils, it clearly demonstrates excellent potential within the fields of tissue engineering and therapeutics.