The efficacy and safety of HA microneedle patches for crow's feet wrinkles

Hyaluronic acid microneedle patch for the improvement of crow's feet wrinkles.

Article specifications

This cinical study was published in 2017 in journal of Dermatol Ther. (IF 2012: 2.83) by Korean dermatologists. The aim of this study was to determine the efficacy and safety of HA microneedle patches for crow's feet wrinkles. We enrolled 34 Korean female subjects with mild to moderate crow's feet wrinkles. Efficacy was evaluated at weeks 2, 4, and 8. Skin wrinkles were measured as average roughness using replica and PRIMOS.

 

Results

Skin wrinkles were significantly reduced and skin elasticity significantly increased in both groups, although improvement was greater in the patch group at week 8 after treatment. In the primary and cumulative skin irritation tests, the HA microneedle patch did not induce any skin irritation. The HA microneedle patch is more effective than the HA essence for wrinkle improvement and is a safe and convenient without skin irritation.