Evaluate the efficacy of a new topical low molecular nano-hyaluronic acid preparation in treating wrinkles, skin hydration, and skin elasticity in humans

Efficacy of a New Topical Nano-hyaluronic Acid in Humans

Article specifications

This Randomized, Comparative, Double musk, Clinical trial was published in 2014 in journal of J Clin Aesthet Dermatol. (IF2014: 1.72) by German dermatologists. The aim of this study was to evaluate the efficacy of a new topical low molecular nano-hyaluronic acid preparation in treating wrinkles, skin hydration, and skin elasticity in humans. Thirty-three subjects were enrolled in the study. The test products that were used (nano-hyaluronic acid in a cream, serum, and lotion) were supplied by the sponsor of the study (Hyalogy® Skincare, DermAvance Pharmaceuticals Inc., Malvern, Pennsylvania). The test materials were applied by the subjects at home, twice daily accordingly to the following instruction: 1 to 1.5mL of the lotion was mixed with 3 to 4 drops of the serum directly in the palm of the hand and applied all over the face, including the periorbital region.

 

Results

The new nano-hyaluronic acid clearly demonstrated a significant benefit in decreasing the depth of wrinkles (up to 40%), and skin hydration (up to 96%) and skin firmness and elasticity were significantly enhanced (up to 55%) at the end of eight weeks.