The efficacy of a single IAJ of a novel HA by measuring the thickness of quadriceps and femoral intercondylar cartilage (FIC) under ultrasonography (US) in addition to subjective self-reported measures

Improvement of self-reported functional scores and thickening of quadriceps and femoral intercondylar cartilage under ultrasonography after single intra-articular injection of a novel cross-linked hyaluronic acid in the treatment of knee osteoarthritis.

Article specifications

This clinical study was published in 2018 in Journal of J Back Musculoskelet Rehabil. (IF 2013:1.39) by Taiwan specialists. The purpose of this study was to evaluate the efficacy of a single IAJ of a novel HA by measuring the thickness of quadriceps and femoral intercondylar cartilage (FIC) under ultrasonography (US) in addition to subjective self-reported measures. Forty-nine patients with KOA (Kellgren-Lawrence grades 2-3) received unilateral IAJ of HYAJOINT Plus to the worse knee and were assessed at baseline and 1, 3 and 6-months after IAJ. Forty-six patients completed the 6-month-follow-up study.

 

Result

All outcome measures improved significantly after HA injection. HYAJOINT Plus is effective both subjectively and objectively for 6 months and is safe as a treatment for KOA.