The long-term efficacy and tolerability of ultrasound-guided intra-articular sodium hyaluronate (MW 1,500–2,000 kDa; Hyalone®) injections in daily clinical practice

Intra-articular injection of hyaluronic acid (MW 1,500–2,000 kDa; HyalOne^®) in symptomatic osteoarthritis of the hip: a prospective cohort study

Article specifications

This clinical trial was published in 2011 in Journal of Arch Orthop Trauma Surg. (IF 2011: 1.84) by Italian specialists. This study investigated the long-term efficacy and tolerability of ultrasound-guided intra-articular sodium hyaluronate (MW 1,500–2,000 kDa; Hyalone^®) injections in daily clinical practice.

 

Results

In real practice HyalOne^® treatment seems to cause a statistically significant reduction in algofunctional indices at 3 months after first injection; at 12 months 80% of the patients achieved a decrease of at least 30% in symptoms. This result may be maintained over time through cyclical and personalized repetition of US guided injections, at least one injection every 6 months.