The effect of a single intra-articular injection of NASHA in the treatment of ankle OA

Nonanimal Hyaluronic Acid for the Treatment of Ankle Osteoarthritis: A Prospective, Single-Arm Cohort Study

Article specifications

This clinical trial was published in 2019 in Journal of Foot & Ankle Surgery (IF 2018:0.19) by Canadian specialists. The purpose of this single-arm cohort study was to determine the effect of a single intra-articular injection of NASHA in the treatment of ankle OA. A single injection was associated with clinically meaningful reductions in pain and disability during a 26-week period and, in general, was well tolerated.

 

Results

The results demonstrate that the injection was generally well tolerated and effective in reducing symptoms. The ankle OA VAS pain score improved significantly, with a clinically meaningful 25% reduction in pain throughout the 6-month follow-up period. Statistically significant improvements were observed in the ankle OA VAS disability score.