Compare the efficacy between single and multiple HA injection formulations

Comparative Effectiveness of Alternative Dosing Regimens of Hyaluronic Acid Injections for Knee Osteoarthritis: A Systematic Review.

Article specifications

This Systematic review was published in 2019 in Journal of Sports Health. (IF 2018:2.649) by American specialists. The purpose of this study was to compare efficacy between single and multiple HA injection formulations.

 

Results

There are limited head-to-head trials comparing viscosupplementation formulations that differ based on number of injections, and in particular, there is a paucity of trials evaluating single-injection formulations. Based on the currently available data, there appears to be similar efficacy with the possibility for greater cost-effectiveness and less patient inconvenience with single-injection formulations.