Evaluate the efficacy and tolerability of a second course of hylan G-F 20 for the treatment of osteoarthritic knee pain over a 12-month period

A second course of hylan G-F 20 for the treatment of osteoarthritic knee pain: 12-month patient follow-up.

Article specifications

This clinical trial was published in 2005 in Journal of J Knee Surg. (IF2005: 0.96) by American orthopedics. The aim of this study was to evaluate the efficacy and tolerability of a second course of hylan G-F 20 for the treatment of osteoarthritic knee pain over a 12-month period in patients who previously experienced a beneficial initial course of therapy. Patients with knee osteoarthritis received 3 weekly injections of hylan G-F 20.

 

Results

A second course of hylan G-F 20 therapy was generally well-tolerated; the types of local events observed in this study were not qualitatively different from those in the current product information and published literature. For continued relief of osteoarthritic knee pain, this study supports repeat use of hylan G-F 20 in patients who had a previous successful course of therapy.