Efficacy and safety of PRGF-Endoret versus hyaluronic acid (HA) as a short-term treatment for knee pain from osteoarthritis

A randomized clinical trial evaluating plasma rich in growth factors (PRGF-Endoret) versus hyaluronic acid in the short-term treatment of symptomatic knee osteoarthritis.

Article specifications

This clinical trial was published in 2012 in Journal of Arthroscopy. (IF:2016: 4.292) by Spanish specialists. The aim of this manuscript is to evaluate and compare the efficacy and safety of PRGF-Endoret (BTI Biotechnology Institute, Vitoria-Gasteiz, Spain), an autologous biological therapy for regenerative purposes, versus hyaluronic acid (HA) as a short-term treatment for knee pain from osteoarthritis.

 

Results

Plasma rich in growth factors showed superior short-term results when compared with HA in a randomized controlled trial, with a comparable safety profile, in alleviating symptoms of mild to moderate osteoarthritis of the knee.