Effects of HA on cell proliferation and synthesis of matrix components of deep flexor tendons

Effects of hyaluronan on cell proliferation and collagen synthesis a study of rabbit flexor tendons in vitro.

Article specifications

This clinical study was published in 1996 in Journal of J Hand Surg Am. (IF 2009: 2.33) by Swedish specialists. This study was designed to assess the effects of HA on cell proliferation and synthesis of matrix components of deep flexor tendons in a well-defined culture system.

 

Results

These findings show that exogenously applied HA may act as a modulator of flexor tendon fibroblast proliferation, indicating a possible mechanism for antiadhesive effects following administration after flexor tendon surgery.