Review article of Hyaluronic Acid in Periodontitis

Hyaluronic Acid and Periodontitis.

Article specifications

This review article was published in 2007 in Acta Medica (Hradec Králové) Journal by czech dentists. The aim of this study is to evaluate the effects of hyaluronic acid in periodontitis.

 

Results

Hyaluronic acid has many important physiological and biological functions and plays a vital role in the functioning of extracellular matrices, including those of the periodontium. It shows anti-inflammatory, tissue healing and bacteriostatic properties. The application of exogenous hyaluronan and hyaluronan-based biomaterials has been successful in manipulating and accelerating the wound healing process in a number of medical disciplines, as evident in ophthalmology, dermatology, and rheumatology. It is also shown to be beneficial in gingivitis and periodontitis therapy owing to its bacteriostatic and anti-inflammatory effects. In conclusion, it is plausible that exogenous hyaluronan administration to periodontal sites could achieve comparable benefits in periodontal healing and surgery, hence aiding in the treatment of periodontal disease.