Safety and wound healing activity of a topical spray powder containing hyaluronic acid (HA) and metallic silver and its effect on the control of bacterial load in vascular ulcers or category I-II pressure ulcers

Hyaluronic acid and metallic silver treatment of chronic wounds: healing rate and bacterial load control.

Article specifications

This clinical trial was published in 2019 in journal of J Wound Care (IF 2018: 1.33) by Italian dermatologists. The aim of this trial was to confirm the safety and wound healing activity of a topical spray powder containing hyaluronic acid (HA) and metallic silver (Hyalosilver, Fidia Farmaceutici S.p.A., Italy), and investigate its effect on the control of bacterial load in vascular ulcers or category I-II pressure ulcers (PU).

 

Results

The data demonstrated good safety and tolerability of the topical spray powder suggesting that the product is effective not only in reducing wound area, due to the presence of HA, but in keeping the bacterial colonisation under control.