Comparison of the effect of of Viscoat (sodium chondroitin sulfate 4%–sodium hyaluronate 3%) and DuoVisc (Viscoat and Provisc [sodium hyaluronate 1%]) on postoperative intraocular pressure

Comparison of the effect of Viscoat and DuoVisc on postoperative intraocular pressure after small-incision cataract surgery.

Article specifications

This prospective, randomized clinical trial was published in 2008 in journal of cataract and refractive surgery (IF 2015:3.02) by Austrian ophthalmologists. In this article the effect of Viscoat (sodium chondroitin sulfate 4%–sodium hyaluronate 3%) and DuoVisc (Viscoat and Provisc [sodium hyaluronate 1%]) on postoperative intraocular pressure (IOP) after bilateral small-incision cataract surgery was evaluated. 60 eyes of 30 patients underwent a small-incision cataract surgery, Each patient’s eyes were randomly assigned to receive Viscoat or DuoVisc during cataract surgery. The intraocular pressure (IOP) was measured preoperatively as well as 1, 6, and 20 to 24 hours postoperatively.

Results

The results of the study showed that Viscoat caused significantly higher IOP increases and significantly more IOP spikes than DuoVisc in the early postoperative period. Therefore, if Viscoat is used during cataract surgery, an additional cohesive OVD should be used for IOL implantation.