Investigate the cytotoxic effect on human corneal epithelial cells and the ability to faciliate corneal epithelial wound healing of carboxymethylcellulose and hyaluronic acid

Comparison of cytotoxicity and wound healing effect of carboxymethylcellulose and hyaluronic acid on human corneal epithelial cells

Article specifications

This clinical trial was published in 2015 in journal of Int J Ophthalmol. (IF2015: 1.14) by south korean ophthalmologists. The aim of this study was to investigate the cytotoxic effect on human corneal epithelial cells (HCECs) and the ability to faciliate corneal epithelial wound healing of carboxymethylcellulose (CMC) and hyaluronic acid (HA).

 

Results

CMC and HA, used in artificial tear formulation, could be utilized without any significant toxic effect on HCECs. Both significantly stimulated HCEC reepithelialization of corneal wounds.