evaluating clinical response to the new CMC-HA eye drop formulation in contact lens wearers

Dual-Polymer Drops, Contact Lens Comfort, and Lid Wiper Epitheliopathy. A Multicenter, Double-masked, Randomized, Clinical study

Article specifications

This Multicenter, Double-masked, Randomized, Clinical study was published in 2016 in journal of Optometry and Vision Science (IF 2016:1.409) by American ophthalmologists. The purpose of this study was to evaluate clinical response to the CMC-HA eye drop formulation in contact lens. 355 subject using one of six types of FDA-approved contact lenses were divided in 2 groups in 2:1 to receive treatment with CMC-HA or CMC 2 drop per eye at least 4 times a day. They examined in day 1 and days 3,30,60,90.

Results

results from the present study showed that both CMC-HA and CMC rewetting drops were safe and well tolerated and regular daily use of a rewetting drop containing both CMC and HA polymers reduces ocular symptoms and associated signs in a wide variety of contact lens wearers. This study demonstrates that the use of a new eye drop containing a combination of CMC and HA during lens wear provides greater improvement in ocular symptoms, and reductions in conjunctival staining and LWE than an existing eye drop containing CMC alone.