The effect of intra-articular injection of HA in patients with RA combined with knee OA

Effect of intra-articular injection of hyaluronic acid in rheumatoid arthritis patients with knee osteoarthritis.

Article specifications

This original article was published in 2008 in journal of J Chin Med Assoc. (IF 2008: 0.82) by Taiwan specialists. The aim of this study was to investigate the effect of intra-articular injection of HA in patients with RA combined with knee OA. Twenty RA patients with OA knees were enrolled; 11 patients were placed into a stage II group and 9 into a stage III group, in accordance with the Kellgren-Lawrence classification of knee OA. All patients received intra-articular injection of HA (ARTZ) once a week for 5 weeks, and were evaluated with the WOMAC index (including the pain, stiffness and physical function subscales) at baseline, week 5 and week 9.

 

Results

Intra-articular injection of HA was beneficial in patients with RA combined with knee OA.