Effect of cd-HA gel on gliding and repair integrity during simulated repetitive motion of a repaired tendon

Tendon surface modification by chemically modified HA coating after flexor digitorum profundus tendon repair.

Article specifications

This clinical trial was published in 2004 in Journal of J Biomed Mater Res B Appl Biomater. (IF 2004:2.15) by American specialists. The purpose of this study was to study the effect of cd-HA gel on gliding and repair integrity during simulated repetitive motion of a repaired tendon in vitro. A total of 36 flexor digitorum profundus (FDP) tendons from six adult mongrel dogs were used and divided into three groups of control, simple HA, and cd-HA.

 

Result

From the 1st cycle to the 10th cycle, there were no significant differences between the three testing groups. From the 50th cycle onwards, however, the friction was significantly lower in the cd-HA gel group than in the control group. The differences between the cd-HA gel group and the unmodified HA group and between the unmodified HA group and the control group were not significant. Neither breaking strength, nor tendon stiffness, nor resistance to gap formation of the repairs was significantly different between the three groups.