Intratympanic Dexamethasone and Hyaluronic Acid in Patients with Low-Frequency and Me´nie`re’s-Associated Sudden Sensorineural Hearing Loss
Intratympanic Dexamethasone and Hyaluronic Acid in Patients with Low-Frequency and Me´nie`re’s-Associated Sudden Sensorineural Hearing Loss
Article specifications
This clinical study was published in 2005 in journal of Otology & Neurotology (IF2015: 0.95) by American Otolaryngologists. This study included 18 patients with isolated low-frequency idiopathic sudden sensorineural hearing loss and 21 patients with sudden sensorineural hearing loss and a history of Me´nie`re’s disease. The acute effect of the intratympanic application of dexamethasone with hyaluronic acid on hearing outcome after failure of an initial standard treatment with intravenous steroid and vasoactive substances was assessed. Evaluation was based on standard pure-tone audiometry findings.
Results
The results of the study showed that Intratympanic combined dexamethasone/hyaluronic acid application provides a reliable and safe therapeutic option for improvement of hearing in patients with isolated low frequency idiopathic sudden sensorineural hearing loss or sensorineural hearing loss resulting from Me´nie`re’s disease who have failed intravenous steroid and vasoactive treatments.
