Sodium hyaluronate eye drops prevent late-onset bleb leakage after trabeculectomy with mitomycin C

Sodium hyaluronate eye drops prevent late-onset bleb leakage after trabeculectomy with mitomycin C. A Comparative, Randomized, Clinical study.

Article specifications

This clinical trial was published in 2008 in journal of eye (IF 2016:2.275) by Japanese ophthalmologists. In this study 68 patients (68 eyes) who had trabeculectomy with MMC were examined in this study. 22 were treated postoperatively with sodium hyaluronate eye drops and 46 eyes were not treated postoperatively (control group). The blebs were classified according to the avascular area, epithelial defect and degree of bleb wall leakage. Both groups were assigned classes 0, avascular or partial avascular bleb; 1, avascular or partial avascular bleb with an epithelial defect; 2, avascular or partial avascular bleb with oozing; 3, avascular or partial avascular bleb with a point of leakage).

Results

The results of the study said that Sodium hyaluronate eye drops can prevent late-onset bleb leakage after trabeculectomy with MMC.